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Moreover, the 2017 Cell paper revealed FOXO4-DRI was able to lower the cellular senescence induced by chemotherapy treatment Doxorubicin: doxorubicin-induced senescent cells showed an upregulation in FOXO4 foci and FOXO4-DRI potently and selectively lowered the viability of doxorubicin-senescent versus control IMR90

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A: mechanisms related to changes in nucleoside metabolism: (1) decitabine inhibits thymidylate synthase (TYMS)

The questionnaire was selected and measured in accordance with the Guidelines for Human Clinical Trials of Hangover Cure Claims established by the Ministry of Food and Drug Safety in Korea [22]