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In animal experiments that exosomal vesicles can modulate the function of T cells and macrophage activity at the maternal-fetal interface, leading to reduced embryo absorption rates and decreasing the likelihood of RM (Xiang et al., 2020)

Another pilot study in 2024 involved 12 women with interstitial cystitis (a chronic bladder pain syndrome) who received BPC-157 injections directly into the bladder wall

The cells were exposed for various times, after which the media was removed and the cells were washed with warm PBS and lysed by brief sonication in fresh PBS

Among women with chronic pelvic pain, prevalence rates reach 35-50%, while infertile women show rates of 25-50% (Giudice, 2010)

30.Smith G.D