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GLS1 is the rate-limiting enzyme responsible for the breakdown of Gln

302 A 2020 clinical trial randomized 40 participants with Parkinson's disease who had motor signs not fully controlled by medication or who were ineligible for deep-brain stimulation in a 2:1 ratio to receive FUS of subthalamic nuclei or a sham procedure as control

Plasma IL-6, its soluble receptors and F2-isoprostanes at rest and during exercise in chronic fatigue syndrome

This stimuli-responsive behavior can be used for selective drug delivery into tumor tissue or cancer cells, thereby improving therapeutic efficiency and reducing side effects (Zhou et al., 2018