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Vitamin B6 is needed for nerves as well as for creating chemical fibers in the body

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During aging, the secretory pattern of hormones produced by the hypothalamic-pituitary axis changes, as does its sensitivity to negative feedback by end hormones, such as the thyroid hormones (T3 and T4), cortisol, estradiol, testosterone, and IGF-1 (van den Beld et al., 2018)

However, accumulation of ergothioneine and increased expression of SLC22A4 in other (injured) tissues have been observed in animal models of liver fibrosis (Reference Tang, Masuo and Sakai46) , fatty liver disease (Reference Cheah, Tang and Ye53) and chronic kidney disease disease (Reference Shinozaki, Furuichi and Toyama54)

Vitamin C has been found to reduce the cholesterol level in patients with hypercholesterolemia (Rossig et al