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Upon confluence of the seeded HCE-2 cells in the culture flask, the cells were trypsinized with Trypsin-EDTA, then trypsinization was stopped with a complete growth medium and cells were harvested, counted and seeded into the six prepared wells

A placebo controlled, randomized double-blind phase II study

Multifunctional cationic lipid-based nanoparticles facilitate endosomal escape and reduction-triggered cytosolic siRNA release

This decrease in enzyme activity can lead to a buildup of a substance called homocysteine in the blood, which is associated with an increased risk of cardiovascular disease, stroke, and other health problems

In fact, myofibroblasts play a crucial role in fibrosis by overproducing ECM components, such as laminin (LN), matrix metalloproteinases (MMPs), and type I, III, and IV collagen proteins, thereby contributing to the thickening and stiffening of pulmonary tissue [14, 15]