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In TC, it was demonstrated that high-mobility group box 1 (HMGB1) mediates autophagy, which promotes NIS degradation via ROS/AMPK/mTOR pathway [232], revealing the cell death-modulating role of ROS

Conclusions During involution, the regulation of organic acids suggests reduced Krebs cycle activity, indicating a transition from high biosynthetic to catabolic activity

also called the phosphogluconate pathway and the hexose monophosphate shunt) is a process that breaks down glucose-6-phosphate into NADPH and pentoses (5-carbon sugars) for use in downstream biological processes

10.1146/annurev.neuro.22.1.123 Annu