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Explaining osteomyelitis and prosthetic joint infections (PJI) in terms of biofilmA review

Application protocol: Product: Hydrocortisone 1% cream (available at any pharmacy without prescription) Timing: Apply after noticing the reaction, not before injection Amount: Thin layer covering the entire affected area plus a 1-centimeter margin Frequency: Twice daily (morning and evening) until the reaction resolves Duration: Typically 2 to 5 days, do not use for more than 7 consecutive days without medical guidance Important: Do NOT apply hydrocortisone before injection, as it can interfere with medication absorption For reactions that do not respond to 1% hydrocortisone, a healthcare provider can prescribe stronger topical corticosteroids (triamcinolone 0.1% or betamethasone 0.05%)

For children aged 13 years, the recommendation increases to 0.5 mcg per day , then to 0.8 mcg per day for ages 46 years, and 1.0 mcg per day for ages 710 years

Interactions with other medications appear minimal based on available data, but comprehensive medication review is essential before starting BPC-157