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Andrology 11 (6), 11321146 (2023)

doi: 10.1016/j.ajps.2020.05.001

Targeting these pathways has emerged as a potential therapeutic strategy to mitigate oxidative damage, reduce inflammation, and improve clinical outcomes in TAO

The citrate buildup lowers ATP synthesis, preventing cellular development under normal physiological circumstances

This lipid metabolic shift, in turn, supports enhanced tumour proliferation and survival, illustrating a novel mechanism by which amino acids (taurine and proline) contribute to lung cancer progression through metabolic reprogramming