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Additionally, dosing at 20 mg/kg body weight or greater resulted in mild to severe fundic lesions on ophthalmologic examination (change in color of the fundus, central or generalized retinal degeneration), abnormal electroretinograms (including blindness), and diffuse light microscopic changes in the retina

Over the past 20 years, lipotropics have become a staple in the weight loss industry

[2] [3] However, reduced effectiveness can have multiple causes, and patients should consult their healthcare provider rather than simply replacing the medication

In DMSO solution: store at 20C, avoid repeated freeze-thaw cycles

All authors have critically discussed the results, revised the manuscript, and approved the final version