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Hypoxia-degradable zwitterionic phosphorylcholine drug nanogel for enhanced drug delivery to glioblastoma

Our study has demonstrated that LPS stimulation induces the upregulation of SLC25A33 via MyD88-dependent PI3K and mTORC1 signaling pathways, leading to M1 polarization

The top 20 metabolites differentiating group A and C involved in nucleotide metabolism (2/20), amino-acid metabolism (3/20), and lipid metabolism (11/20)

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Cells overcome this oxidative stress via anti-oxidant defence mechanisms that include Superoxide Dismutase (SOD), Glutathione Peroxidase (GPx), Catalase (CAT), Glutathione (GSH), and peroxiredoxins