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Additionally, the potential of AS-IV to mitigate toxicity when co-administered with anticancer drugs is explored, highlighting its broader therapeutic applicability and role in optimizing polypharmacy strategies for improved patient outcomes (Figure 2)

Researchers use an aspartate analog to mimic EAAT2 inhibition.[ref] Note that aspartame (artificial sweetener) contains aspartate plus phenylalanine

Water was purified using a Milli-Q system (Millipore, United States)

4 , e36 (2013)

We developed benzoxazole compounds with aromatic (phenyl, naphthyl, and biphenyl groups) and heteroaromatic (pyridine, pyrrole, furan, and thiophene) groups in the 2-position of benzoxazole to increase PAS binding potential for AChE in our fragment-based strategy