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Science 381 , 10921098 (2023)

In the presence of another reductant, Compound II will return to the resting state (Glorieux and Calderon 2017)

A path to translation: How 3D patient tumor avatars enable next generation precision oncology

Running 8-week cycles with 4-week breaks means approximately 8 months of active use per year rather than 12

These complexes detect danger signals such as PAMPs and DAMPs, leading to the activation of caspase-1 and the maturation of pro-inflammatory cytokines IL-1 and IL-18