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10.1136/annrheumdis-2021-221796 28 TanJ

Recent development of KRAS G12C inhibitors (e.g., sotorasib, adagrasib) has opened new therapeutic avenues, and combining these with metabolic inhibitors represents a promising strategy to overcome resistance [55, 56]

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A double-blind, placebo-controlled study published in the Journal of Pakistan Association of Dermatologists found that 1,200 mg of intravenous glutathione administered twice a week for 6 weeks resulted in visible skin tone lightening in 37.5% of participants