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Other ruthenium complexes, such as cis-[Ru(dcbpyH)2(PTAH)2]Cl2, cis-[Ru(bpy)2(PTA)2]Cl2 and trans-[Ru(bpy)2(PTA)2](CF3SO3)2, exhibited 4- to 10-fold increase in cytotoxicity upon photoactivation in lung cancer A549 and prostate adenocarcinoma PC-3 cells [91]

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This imbalance between oxidants and antioxidants may contribute to the development of pulmonary function abnormalities and disease progression [7]