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doi: 10.1016/0049-0172(73)90035-8 17 FredrikssonTPetterssonU

13 reasons why the brain is susceptible to oxidative stress

In this study, we attempted to evaluate whether the GSH precursor, GGC, could increase GSH levels in primary astrocytes and protect primary astrocytes against biomarkers of apoptosis and cell death, oxidative stress, and neuroinflammation when exposed to pathophysiological concentration of oligomeric A 40

Apart from the common ALA and vitamins in practice, other antioxidants, although not yet widely used, also show potential in treating neurological diseases

Free Radic Biol Med 122: 116- 129 Terai Y, Ueno H, Ogawa T, Sawa Y, Miyagi A, Kawai-Yamada M, Ishikawa T, Maruta T (2020) Dehydroascorbate reductases and glutathione set a threshold for high light-induced ascorbate accumulation