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Additional information Edited by G Melino Supplementary Information accompanies this paper on Cell Death and Disease website Rights and permissions Cell Death and Disease is an open-access journal published by Nature Publishing Group

[13] [19] Specifically, the function of GSTs in this role is twofold: to bind both the substrate at the enzyme's hydrophobic H -site and GSH at the adjacent, hydrophilic G-site, which together form the active site of the enzyme

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Muthusami KR, Chinnaswamy P

Importantly, BPC-157 also induces expression of EGR-1 and its corepressor NAB2, forming a regulatory feedback loop that modulates the duration and amplitude of angiogenic gene transcription during wound healing