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Seven studies classified PA as elevated DHEA(S) compared to age-matched peers or controlled for age when assessing the effects of DHEA(S) levels (, , , , ), two used specific cutoff values to split children into PA and non-PA groups (, ), and seven assessed DHEA as a continuous variable while controlling for age or utilizing a narrow age range ()

Through these combined actions, GHK-Cu not only supports skin rejuvenation but also contributes to overall skin vitality, making it a valuable component in both cosmetic and therapeutic applications aimed at enhancing skin health and appearance

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