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This is an interesting study and an area that should be investigated, given B12 links to neurological health

In that study, a compensatory induction of keratinocyte lipid-binding protein was observed that was reported to overcome the functional effects of loss of adipocyte-specific aFABP/ALBP/aP2 (110)

During the treatment of CIA rats, we found that the HA-Lipo@G/D treatment group significantly reduced the expression of inflammatory factors IL-6 and TNF- while concurrently upregulating the anti-inflammatory IL-10 level in plasma

7b, c), consistent with the observations in our cell culture studies

Serum levels of insulin-like growth factor I and its binding proteins in health and disease