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Gallic acid protects intervertebral disc cells from ferroptosis and alleviates intervertebral disc degeneration by regulating key factors of oxidative stress

Reactive oxygen species can damage cells in many ways: by inactivating proteins, damaging nucleic acids, and altering the fatty acids of lipids, which leads in turn to perturbations in membrane structure and function

GSH fights free radicals, toxins which can damage at cellular level

The peroxiredoxin and glutathione peroxidase families in Chlamydomonas reinhardtii

Our results demonstrated that TG2 mediates GST tag crosslinking or polyamination and causes aggregate formation