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Fibroblast growth factor 21 reverses hepatic steatosis, increases energy expenditure, and improves insulin sensitivity in diet-induced obese mice

Reduced accumulation of specific microRNAs in colorectal neoplasia

Macrophages exposed to choline deficiency or ChoK inhibitors (MN58b or RMS932A) exhibit poor PC and sphingomyelin mitochondrial membrane composition, leading to defective mitochondrial ATP synthesis that boosts AMPK activation and mitophagy ( Figure 3 )

These signals attach to TLR4 and other TLRs on Kupffer cells and trigger the release of proinflammatory cytokines, such as TNF, chemokines, and reactive oxygen and nitrogen species (140)

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