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DNA hypo-methylation and expression of GBP4 induces T cell exhaustion in pancreatic cancer

Regulation of the CNC-bZIP transcription factor Nrf2 by Keap1 and the axis between GSK-3 and -TrCP

In rats, AC exhibits an oral bioavailability of only 0.12%, with Cmax values ranging from 0.13 to 135.4 ng/mL and short half-lives of 10.7 to 92.1 min

Astrocytes are central to this process: lactate produced by astrocytes is transported into neurons via monocarboxylate transporter MCT2, where lactate dehydrogenase B (LDHB) converts it to pyruvate

Researchers have discovered that patients who took isotretinoin also tend to have elevated levels of a certain enzyme called creatine phosphokinase (or CPK)