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The convergence of advanced gene editing technologies, precision metabolomics, single-cell multi-omics, and artificial intelligence-driven drug discovery holds particular promise for transforming our understanding of mitochondrial neurodegeneration into clinically meaningful therapeutic advances in the coming decade

Bhatt, P

Sci Rep 3:1199

Hoboken, NJ: Wiley, pp

Inflammatory factors and oxidative stress damage the intestinal mucosal barrier, leading to reduced expression and impaired function of tight junction proteins, as well as increased intestinal permeability