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Description

d , Volcano plot of the combined chromosome arm screen using a model-based analysis pipeline

5 , e004510 (2016)

In a first screening, NTS were incubated for 72 h at the highest concentration (100 M) of PZQ, AS, NAC and RESV alone and combined (e.g

Amino acid synthesis Fmoc-protected SetCys amino acid was synthesized from cysteine methyl ester hydrochloride in five steps with 55% overall yield, as described in the Supplementary Methods section and in Supplementary Fig