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Necroptosis, pyroptosis and apoptosis: an intricate game of cell death

Vallespinos M, Fernandez D, Rodriguez L, Alvaro-Blanco J, Baena E, Ortiz M, et al

ROS generated during oxidative stress can activate the IB kinase (IKK) complex, which phosphorylates IB proteins and marks them for ubiquitin-mediated degradation