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This leads to irreparable oxidative damage to bacterial cell membranes and other functional biomolecules such as DNA, enzymes, and fatty acids, thereby exerting cytotoxic effects on both bacteria and tumor cells

1,23 For example, HSP70 and HSP90 are known to interact with key autophagy regulators such as Beclin-1 and LC3

The ensuing lactate from the subsequent lactate dehydrogenase reaction can also lead to the generation of glucose in the liver of the tumor-hosting patient through the Cori cycle (Fig