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Journal of Biological Chemistry 277, 44765-44771CrossRefGoogle ScholarPubMed 77Shih, A.Y., Erb, H., Sun, X

239 The body increases thermogenesis, primarily through non-shivering thermogenesis in brown adipose tissue, which involves increased FAO and uncoupling of OXPHOS to generate heat rather than ATP

A deeper understanding of the mechanisms of ROS interactions originating from different sources, such as mitochondria and NADPH oxidase, may open new avenues for therapeutic interventions in angiogenesis-related cancer and other chronic diseases