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Western blotting results confirmed that LOXL2 expression was highest in aortic tissues of old WT mice and lowest in those of young LOXL2+/ mice (Fig

10.1016/j.isci.2022.105401 iScience 150 SinghA.Erwin-GrabnerT.Goya-MaldonadoR.AntalA

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Indeed, based on the recently released EULAR (European League Against Rheumatism) points to consider on PsO to PsA transition, it is possible to identify a phase of psoriasis at higher risk for PsA that is typified by medium- to long-term risk factors (average of 712 years before PsA onset), including severe skin involvement, nail psoriasis, obesity and familial history for PsA, and a phase of subclinical PsA encompassing short-term risk factors (average of 13 years before PsA onset), including arthralgia and imaging evidence of synovio-entheseal inflammation (Fig