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(Qiu et al., 2023) reported low levels of NAD + in the aorta from hypertensive patients showing that supplementation with NAD + precursors effectively lowered blood pressure and improved impaired vascular function in both hypertensive patients and mice

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Yangs group (2024) published a new anti-EGFR lenalidomide-based PROTAC 81 capable of degrading the EGFR C797S mutant protein for the treatment of lung cancer