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Although the mechanisms involved in their involvement are not clear at the moment, which are our immediate challenge to overcome

The acquisition of viable autologous IVD cells is also problematic: harvesting cells from healthy discs risks iatrogenic damage, while cells derived from degenerated discs often exhibit reduced viability and functionality

Nevertheless, two placebo-controlled crossover studies demonstrated that 2 months of folate supplementation improves endothelial function in hyperhomocysteinemic subjects by decreasing homocysteine levels (Bellamy et al, 1999

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Those in care homes require systems to ensure regular maintenance injections are not missed