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References Campbell, R., Bellolio, F., Motosue, M., et al

All Y receptors desensitize by clathrin-mediated endocytosis in complex with the bound ligand after activation

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( a - d ) Observed mean percentage change from baseline over time for participants in the full analysis set during the in-trial observation period in waist circumference (a), systolic blood pressure (b), diastolic blood pressure (c), and HbA 1c (d)