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This convergence renders the NF-B and C/EBP pathways promising drug targets for the modulation of the SASP

Importantly, integrating autophagy modulation with immunotherapy is emerging as a novel approach

507 The brains of individuals with preclinical AD (PCAD) and AD exhibit oxidative damage to a variety of molecules, e.g., accumulation of protein carbonyls (PCs) in regions that are rich in A-peptide-containing SPs, increased lipid peroxidation in AD and PCAD hippocampi and elevated DNA damage