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However, despite its advantages in offering a detailed network of pharmacological activity, challenges remain, particularly in managing large datasets and refining existing methods to improve accuracy and reliability [71]

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All TrxR enzymes require an NADPH-dependent reduction step to exert their function in vivo and TrxR is a therapeutic target for cancer and infectious diseases 21,67

Occasional small amounts of alcohol might be okay, but drinking alcohol regularly or in large quantities increases the risk of stomach bleeding and liver damage when combined with ibuprofen