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We consider this discrepancy stems from the unique in vivo pharmacological advantages of nanobodies with its small size enabling a deeper tumor penetration

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As noted earlier, many of these early model studies that suggested the importance of Fc-dependent effector functions also found that protection was independent of complement, leading to a greater focus on FcR-mediated interactions 87

PMID: 7286900, DOI: 10.1002/hep.1840010302

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