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Using Lorke's method for assessing acute toxicity in mice, both the leaf extract and flavonoid-rich fraction of C

Acknowledgements This work was financially supported by the National Natural Science Foundation of China (81870423 and 82073914), the Major Project of the Natural Science Research of Jiangsu Higher Education Institutions (19KJA310005), the Open Project of Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica (JKLPSE202005, JKLPSE201815, and JKLPSE 201804), the Project of the Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD), and the Postgraduate Research & Practice Innovation Program of Jiangsu Province (SJCX20_0536 and KYCX20_1493)

Cancer-related inflammation

NPRL2 gene therapy induces effective antitumor immunity in KRAS/STK11 mutant anti-PD1 resistant metastatic non-small cell lung cancer (NSCLC) in a humanized mouse model