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Gamma-glutamyl transpeptidase (GGT) plays key roles in GSH homeostasis by breaking down extracellular GSH and providing cysteine, the rate-limiting substrate, for the intracellular de novo synthesis of GSH

P.MohammedS.et al (2024)

Therefore, inhibiting the function of TXN and TXNRD disrupts the redox balance in cancer cells, leading to heightened oxidative stress and subsequent cell death [54]

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10.1016/0006-2952(61)90145-9 17 EnayatiA