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Melasma is a chronic skin condition characterized by brown or gray-brown patches on sun-exposed areas, especially the face

Plant Cell [Internet]

We have developed a novel, stable formulation of reduced glutathione for oral delivery (sold as ReadiSorb liposomal reduced glutathione by YES, LLC of Palo Alto, Calif.) and report that liposomal encapsulation markedly enhances the cellular bioavailability of reduced glutathione, meaning the novel, stable formulation is both storable for long periods and survives oral administration, and as a result, intracellular glutathione is enhanced and achieves results not achievable by non-intravenous administration of either plain glutathione (in any form) or non-liposomal reduced glutathione (which is normally largely oxidized in the gastrointestinal tract)

Hosnijeh FS, Siebuhr AS, Uitterlinden AG, Oei EH, Hofman A, Karsdal MA, et al

The reality is more nuanced and formula-dependent