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Brittenham 2008), further exacerbating the detrimental impact of aging in our body

Cell, 70(1), 5-8

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Furthermore, metformin exerted two supplementary beneficial effects through the AMPK-determined PEN2-ATP6AP1 axis, specifically diminishing hepatic lipid accumulation in mice liver and prolonging the lifespan of Caenorhabditis elegans , in addition to this postprandial glucose reduction (8)