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Severe Heavy Metal Sensitivities: While not as clear-cut as Wilson's disease, a known, severe allergy or sensitivity to copper or other heavy metals is a major red flag

This requires expensive equipment and technical knowledge

GHK-Cu increases production of superoxide dismutase (SOD), one of the body's most important antioxidant enzymes

In addition to the glutathione side effects above, injectable GSH use can cause redness, swelling, or bruising at the injection site

Additionally, the state and limitations of clinical validation of aging biomarkers (eg, p16^INK4a, -galactosidase) remain major hurdles for translation