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European Journal of Endocrinology , 1998 Established Ipamorelin's selectivity for GH secretion without significant cortisol or prolactin elevation

Whilst there was a reduction in systolic and diastolic blood pressure in all groups, this was only significant from baseline in the group who received the standard triple therapy and broccoli sprout powder combination (14 and 9.4 mmHg reduction in systolic and diastolic blood pressure, respectively) (Mirmiran et al., 2014)

Pairing it with GHRP-6 would introduce significant cortisol and prolactin elevation from the GHRP component, partially offsetting the clean endocrine profile of CJC-1295

Ipamorelin Selectively activates ghrelin receptors, stimulating GH release without significant effect on other pituitary hormones. Often studied alongside CJC-1295 for combined effects

A pre-ranked gene list of the Bru-Seq data set was submitted to GSEA, and enrichment analysis was done based on the KolmogorovSmirnov statistic 59,60