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The APX expression is also affected by SA when externally applied by increasing APX and GR activity, which increases salt tolerance in mung bean (Narendra et al., 2006

Sirt1 played a key role in mitochondrial biogenesis by upregulating PGC1 expression [67]

Inflammatory cytokine evaluation (IL-6 and IL-10) Levels of interleukin-6 (IL-6) and interleukin-10 (IL-10) were quantified using commercial ELISA kits (R&D Systems, Minneapolis, MN), according to the manufacturers protocol as referenced by Mrmora et al

Additionally, the knockdown of SMAD proteins via RNA interference leads to an upregulation of apoptosis markers, thereby confirming that the therapeutic effects of hADSC-Exos are mediated through the SMAD pathway