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It's common in partial hospitalization programs, intensive outpatient programs, and substance use disorder programs

doi: 10.5217/ir.2015.13.1.11

In a study on HCC cell lines and mouse models with in situ tumors, it was shown that MET activation can phosphorylate the 56th tyrosine residue and trigger glycogen synthase kinase 3 (GSK3), resulting in decreased PD-L1 expression [137]