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Samaraweera et al., 2024

More recently, in 2022, a genome-wide association study (GWAS) with 130 lipedema carriers identified six gene regions associated with body shape, lipoma formation, adiposity, and sex hormone biology, including the genes CPE , ZNF25 , and ZNF33A , which are related to estrogen biology 24

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Furthermore, an on-farm trial demonstrated that supplementing dairy cow diets with extruded flaxseed raised the levels of beneficial omega-3 FAs in milk [15]

They may have tried dietary changes, supplements, or even stimulant medications, but still feel mentally dimmed. These individuals may have underlying oxidative stress or mitochondrial inefficiencies contributing to their cognitive symptoms