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IGF-1 LR3 enhances nutrient partitioning, directing nutrients toward muscle cells and away from fat cells, supporting both muscle growth and fat reduction

Extensive peroxynitrite activity during progressive stages of central nervous system inflammation

However, acutely after an ischemic stroke, elevated glutamate levels combined with changes in the Na + concentration trigger a reversal of the high-affinity Na + -dependent glutamate transporters, further contributing to the extracellular accumulation of glutamate (Longuemare and Swanson, 1995