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Epidermal growth factor receptor (EGFR) upregulation is eventually caused by the activation of several signaling pathways, including the Nuclear factor kappa B (NF-kB), Mitogen-activated protein kinase (MAPK), and phosphoinositide 3 kinase (PI3K)/Akt/mammalian (or mechanistic) target of rapamycin mTOR pathways

Mancozeb exposure during development and lactation periods results in decreased oocyte maturation, fertilization rates, and implantation in the first-generation mice pups: protective effect of vitamins E and C

Sep-Oct 2003;54(5):531-9

A randomized, double-blind, placebo-controlled clinical study evaluating the efficacy of a line-targeting peptide serum in improving expression lines and skin health

Consistent with the data in mice, the activation of circulating neutrophils as an indicator for the activation status of hepatic neutrophils showed no neutrophil activation during the injury phase but substantial activation (ROS, phagocytosis) selectively during the recovery phase [98]