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Mol Cancer Ther (2019) 18:87385

Other preferred oligonucleotides comprise one of the following at the 2 position: C 1 to C 10 lower alkyl, substituted lower alkyl, alkaryl, aralkyl, O-alkaryl or O-aralkyl, SH, SCH 3 , OCN, Cl, Br, CN, CF 3 , OCF 3 , SOCH 3 , SO 2 CH 3 , ONO 2 , NO 2 , N 3 , NH 2 , heterocycloalkyl, heterocycloalkaryl, aminoalkylamino, polyalkylamino, substituted silyl, an RNA cleaving group, a reporter group, an intercalator, a group for improving the pharmacokinetic properties of an oligonucleotide, or a group for improving the pharmacodynamic properties of an oligonucleotide, and other substituents having similar properties

Many patients consider it as part of a broader regenerative approach alongside stem cell therapy, including treatments using umbilical cord stem cells

Another study found that EGCG can reverse homocysteine-induced neurodegeneration and neuroinflammation in hyper-homocysteinemic rats

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