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Mol Med 20(1):2152120

However, keep in mind that research in humans is needed

Definition: Histamine

For example, an early in vitro study demonstrated that inactivation of PHD2, which increased HIF-1 activity, could promote vessel normalization and mitigate potential cardiotoxicity associated with cancer treatments [273]

Working within that intellectual tradition at the University of Zagreb School of Medicine, a group led by Predrag Sikiri proposed that human gastric juice itself contained protein mediators of this protective response