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Approach Phase 2b trial arm Duration 24 weeks Review Point Week 12 and 24 Notes METAOD006 (OPTIONS) used 24 weeks at oral doses 0.25, 0.5, or 1 mg/day in 502 obese adults

Enhanced MSC recruitment potentially increasing osteoblast and chondrocyte numbers at healing sites

For I have 3 three questions: 1) Have you seen a way to equate dosages between oral form and subcutaneous injection to help determine what dosages correspond to each form

They are not statements about what would happen in any individual person