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Effect sizes were derived using a predefined formula based on differences in means and standard deviations

The search strategy employed a combination of the following keywords and MeSH terms: Parkinsons disease, ferroptosis,lipid peroxidation, alpha-synuclein, microglia, astrocytes, therapeutics, and neuroprotection. The inclusion criteria focused on original research articles, reviews, and clinical trials published in English that elucidated molecular mechanisms, pathological features, or therapeutic strategies related to ferroptosis in PD

(72), utilizing data-independent acquisition (DIA) proteomics, analyzed 190 blood samples and found that patients with acute myocardial infarction (AMI) complicated by malignant ventricular arrhythmia (MVA) exhibited decreased plasma levels of TGFBI and increased levels of vWF, both of which can be candidate biomarkers for MVA