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ROS stimulates the extrinsic apoptotic pathway by promoting the ubiquitin degradation of the cellular FADDlike IL1converting enzymeinhibitory protein (cFLIP), which inhibits the formation of deathinducing signaling complex (DISC) via competitively combining with FADD [150]

Breakthroughs in glutaminolysis for diagnostic and therapeutic applications in autoimmune diseases are future research areas, and glutaminolysis may be a new therapeutic strategy for autoimmune diseases