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The enhancement of cardiotoxicity that results from inhibiton of CYP 3A4 activity and hERG channel by berberine in combination with statins

doi: 10.1016/j.neuroscience.2012.11.021 354 Halon-GolabekMBorkowskaAKaczorJJZiolkowskiWFlisDJKnapNet al

A study examining plasma samples from 50 migraine patients and 30 healthy volunteers found that plasma levels of 8-hydroxy-2-deoxyguanosine were significantly higher in migraine patients compared to controls, indicating a connection between migraine and oxidative stress-related DNA damage (Geyik et al., 2016

At the systemic level, adipocyte-specific deletion of p53 augmented the response to IF, which was accompanied by a de-repressed lipid catabolic and oxidative state of adipocytes upon p53 KO in comparison to controls

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